Creating wireframes is an integral part of the design process. I use them to help facilitate user testing, both in basic sketches as well as wireframes made in Balsamiq, Axure and Illustrator. A lot of big usability issues are often found in the wire framing stage and can be corrected quickly, saving everyone a lot of time, money and wasted resources. Below are some wireframe examples, sensitive information removed or obscured.
Wireframes created for PCI Universities PCI-Q using Balsamiq.
Wireframes created for the depression health center. This is one of several versions that were mocked up.